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Glibenclamide Bp Gujarat

1] Technologies:

1A] Unit Operations:

At Elixir Pharma, we routinely carry out following operations:

  • Reaction ( a total of 50,000 lit reactor volume)
  • Filtration
  • Crystallization
  • Drying (Tray Dryers, VTD, FBD, RCVD)
  • Milling/Micronization
  • Sifting
  • Blending

1B] Process Capabilities:

Process Description
Bromination Liquid bromine, HBr
Chlorination Chlorine gas, Thionyl chloride, Hcl
Concentrated peroxides Perform oxidation using H2O2
Cyclopropanation Using Ethyl Diazoacetate
Diazo Compounds EDA
Elemental reactive metals Expertise with Sodium, Magnesium, Zinc etc
Lithiation Lithiation using n-BuLi, LDA
Azide NaN3
Oxidation Jone’s, Swen’s, Prinz, KMnO4, MnO2, NaOCl, Oxone etc.
Phosgenation Using Triphosgene
Reduction Metal–ammonia, sodium borohydride, borane dimethylsulphide etc.
Chlorosulfonation Chlorosulfonic Acid
Carbamate Formation Isocyanates

1C] Reaction Capabilities:

At Elixir Pharma, we have expertise in carrying out following reactions:

  • High Temperature Reactions (up to 300 0C)
  • Cyclization
  • Friedel Crafts Reaction
  • Condensation
  • Hazardous Reactions  (AlCl3; DEZ; DIBAL; nBuLi; SOCl2;ClSO3H NaN3)
  • Reformatsky Reaction
  • Grignard
  • C-C Bond Formation/Suzuki Coupling
  • Borane Chemistry
  • Swern Oxidation
  • Homologation Reaction/Matteson Reaction
  • Perkin Reaction
  • Coupling/De-coupling Reactions (BOC, F-Moc, CBZ etc)